Iterative deconvolution technique for measurements of diffraction-limited images on optical microscopes

Iterative deconvolution technique for measurements of diffraction-limited images on optical microscopes

Diffraction limit is usually a thorny problem in an optical inspection system. In this investigation, a model-based deconvolution technique was developed to recover diffraction-limited images, where images with sizes smaller than the diffraction limit could be recognized. Experiments were carried out with a traditional microscope at 200× magnification coupled with a halogen light source for a s...

Accelerated iterative blind deconvolution of still images

Deconvolution and Restoration of Optical Endomicroscopy Images

Optical endomicroscopy (OEM) is an emerging technology platform with preclinical and clinical imaging utility. Pulmonary OEM via multicore fibres has the potential to provide in vivo in situ molecular signatures of disease such as infection and inflammation. However, enhancing the quality of data acquired by this technique for better visualization and subsequent analysis remains a challenging p...

Low sidelobe limited diffraction optical coherence tomography

Optical Coherence Tomography (OCT) is a relatively new type of imaging system for medical diagnosis. Because most current OCT systems use a sharply focused beam in tissues, they have a short depth of field (high image resolution is near the focus only). In this paper, limited diffraction beams of different orders are used to increase depth of field and to reduce sidelobes in OCT. Results show t...

Optical diffraction for measurements of nano-mechanical bending

We explore and exploit diffraction effects that have been previously neglected when modelling optical measurement techniques for the bending of micro-mechanical transducers such as cantilevers for atomic force microscopy. The illumination of a cantilever edge causes an asymmetric diffraction pattern at the photo-detector affecting the calibration of the measured signal in the popular optical be...